Does the long-term use of Tramadol 100mg have any side effects?

Does the long-term use of Tramadol 100mg have any side effects?

Tramadol 100mg has a greater risk of misuse and addiction than many people know. Addiction, once established, can cause significant physical and psychological damage.

The Long-Term use of Tramadol 100mg

Tramadol 100mg isn’t always the first thing that comes to mind when we learn about taking opioids. Tramadol 100mg has traditionally been thought to be the safest medication on the market, particularly in contrast to high-profile opioids including OxyContin and Fentanyl, the dangers of overdose to which are commonly recognised also for many with just a cursory understanding of substance misuse. In fact, after nearly two decades of evidence showing substantial misuse potential, tramadol 100mg was not even listed as a schedule IV-controlled drug until 2014. Tramadol 100mg Online

Of course, if you are suffering from tramadol 100mg withdrawal, you are well aware of its toxic existence. What you may not be sure of are the dangers that come with the addiction.

Tramadol, also known as Ultram, has been largely unknown in the field of addiction, in part because it is an atypical drug that is not technically classified as a narcotic. However, like most opioids, it comes with a slew of risks, particularly as tolerance builds and you progress to higher doses over time.

When your dosage rises, so does your chance of experiencing short-term side effects such as nausea, dizziness, vertigo, vomiting, and constipation. Although they do not seem to be important at first glance, they may have an impact on the quality of life and functionality.

Long-term tramadol usage, on the other hand, may have far-reaching consequences:


Tramadol 100mg has been linked to epilepsy in some users. Although those with epilepsy are at a higher risk, seizures can occur even in those with no previous history of seizures. Although high doses can raise the risk of seizures for others, a number of studies “demonstrate that seizures can also occur in therapeutic ranges—particularly when combined with other drugs such as alcohol, selective serotonin reuptake inhibitors, tricyclic antidepressants, and antipsychotics.” Seizure risk is calculated to be between 8 and 35 percent overall, but evidence shows the risk rises with time, making long-term users especially vulnerable.  Tramadol 225MG Online

Adrenal Insufficiency:

The adrenal glands are endocrine glands that produce hormones such as cortisol, adrenaline, and aldosterone. These hormones play a number of important roles, including regulating blood pressure and heart rate, helping the body to properly metabolise foods, and preserving immune system function. Chronic tramadol 100mg use has been linked to adrenal insufficiency, which means the body’s capacity to manufacture certain drugs is impaired. As a consequence, a variety of essential functions are jeopardised, and you can suffer symptoms such as muscle exhaustion, nausea, and a loss of appetite.

Androgen Insufficiency:

Androgens are sex hormones, specifically testosterone, that have been linked to secondary sex characteristics in males, as well as bone and muscle growth, metabolism, and sexual and reproductive health. According to research, long-term opioid use, like tramadol 100mg, will lower these sex hormone levels and trigger androgen insufficiency. This can result in a variety of symptoms such as lack of libido and sexual enjoyment, fertility issues, reduced muscle and bone density, and mood disorders such as depression. Although androgen deficiency is often associated with and researched in men, it can also affect women and cause much of the same symptoms.

Respiratory Problems:

Although the risk of respiratory failure with tramadol is not as serious as with other opioids, it can induce heavy and shallow breathing. As a result, fainting, dizziness, and confusion can occur. The use of alcohol, benzodiazepines, or hypnotics increases the risk of respiratory depression.


Although untested, case stories of tramadol-induced hallucinations, especially in elderly users, exist.

Serotonin Syndrome:

Serotonin syndrome is caused by abnormal serotonergic activity, which disrupts normal central nervous system function. As a result, you can feel anxiety, lack of muscle function, accelerated heart rate, stiff muscles, sweating, and problems with coordination. Tramadol 150mg Online

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